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| Brand | MultiSciences |
| CatNum | 70-EK1117 |
| Product Name | Human VEGF R1/Flt-1 ELISA Kit |
| Customs Name | Human VEGF R1/Flt-1 ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4 (unopened) standard stored at -20, others stored at 4 (opened) |
| Shipping Condition | 4 |
| Sample Volume | 20 l |
| Sensitivity | 6.99 pg/ml |
| Standard Curve Range | 156.25 - 10000 pg/ml |
| Spike Recovery Range | 96 % - 114 % |
| Mean Spike Recovery | 0.99 |
| CV of Intra plate | 4.6 % - 5.5 % |
| CV of Inter plate | 2.9 % - 4.6 % |
| Release Date | 2015/11/26 |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against VEGF R1 Human VEGF R1 Standard, lyophilized VEGF R1 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10) Substrate (TMB) Stop Solution Washing Buffer (20) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human VEGF R1. The Human VEGF R1/Flt-1 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Vascular endothelial growth factor receptor-1 (VEGF R1), also known as Flt-1, is a receptor tyrosine kinase (RTK) specific for the angiogenic factors VEGF (VEGF-A), PlGF, and VEGF-B. There are two forms: membrane - bound (mbVEGFR) and soluble (sVEGFR), depending on alternative splicing. Experimental and clinical administrations of sVEGF R1 have been employed successfully in the prevention of neovasculogenesis and tumor growth. The serum/plasma level of sVEGF R1 may vary by pathology, and may have prognostic value. It has been suggested that sVEGF R1 levels should be presented alongside VEGF levels in experimental and pathological conditions. High levels of sVEGF R1 reportedly occur in the plasma during pregnancy and in patients with essential hypertension. Significantly lower levels have been observed in the plasma of patientswith cardiovascular disease and in smokers. |
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